3D CELLULAR IMAGING

What you will find in this eBook

The widespread use of 3D cell models that mimic the in vivo cellular environment has reshaped cell culture assays in recent times. These complex and biologically relevant 3D cell cultures offer excellent opportunities to perform predictive assays during early-stage drug discovery.

This eBook provides a collection of applications and case studies using the ImageXpress® Micro Confocal High-Content Imaging System and MetaXpress® software to investigate diverse 3D models and resolve common challenges experienced in 3D cell culture assays.

Learn how to:

• Image a wide variety of 3D cell culture models, such as spheroids and organ-on-a-chip
• Improve precision and quality with water immersion objectives
• Overcome the challenges of image acquisition and analysis – reducing time to discovery

Sample pages

Imaging of 3D cancer spheroids

Characterization of angiogenesis in organ-on-a-chip model

High-throughput imaging assays using zebrafish

3D toxicity assay using iPSC-derived hepatocyte spheroids

Water immersion objectives