Talking Techniques | Organoids: advancing drug discovery and cancer research
"As the transition from 2D to 3D cell cultures, or organoids, as the gold standard for modeling basic biology and disease continues, these models are being utilized in ever more intricate and impactful ways.
This episode covers the rise of organoids and their advantages over 2D cell cultures, before exploring just how representative these models are becoming and their new applications in drug discovery. To discuss all this and more, [Tristan Free, Digital Editor at BioTechniques interviews] Oksana Sirenko, Senior Scientist at Molecular Devices, who works extensively with the company’s organoid model development programs.
Oksana reveals the potential of these models in cancer therapeutics, driven forward by new patient-derived organoids, and notes the challenges presented by imaging these thicker, 3D models. We also explore the potential discoveries that can be unlocked by combining organoids with organ-on-a-chip models."