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Application Note

Optimization of NaV1.5 channel assay with FLIPR Membrane Potential Assay Kits

  • Study changes in membrane potential brought about by compounds that modulate or block voltage-gated ion channels
  • Reduce assay variability using quench technology to remove wash steps
  • Optimize assays with a choice of two quench technologies
  • 检测由调控或阻断电压门控离子通道的化合物引起的膜电位变化
  • 最大化细胞系/通道/化合物的适用性以消除数据中存在的差异性